Skin cancer biomarkers
نویسندگان
چکیده
Skin cancer is the most common type of cancer and there are two forms: melanomas and melanoma (basal cell carcinoma and squamous cell carcinoma). The main risk factor in both types of skin cancer is exposure to sunlight and other sources of ultraviolet radiation. In comparison with basal or squamous cell carcinoma melanoma skin cancer is less common but more serious if not treated early, and can lead to death. Non melanoma skin cancer, the most common human cancers in which incidence of basal cell cancer (BCC) are 80-75 % and up to 25% is squamous cell (SCC). Due to the rise in skin cancer in recent decade’s diagnosis and treatment has become more important. Non melanoma skin cancer is the most common cancer in Iran which current method of diagnosis is invasive biopsy, a procedure in which detection take place after entire formation of cancer. Bleeding, infection, scar formation and scar are disadvantages of this method that motivate the researchers to investigate noninvasive method during the last decade, in addition early detection of cancer, leading to more effective treatment. Positron Emission Tomography (PET), nuclear resonance imaging (MRI) and Raman spectroscopy are noninvasive skin cancer instrumental detection methods. In this research plan, based on scientific data obtained from biochemical changes in cancer cells, we consider to investigate and invent a non-instrumental method for early detection with universal application. Keywords— Skin cancer, non-melanoma skin cancer, noninvasive detection, early detection
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